Good And Suitable Temperature Resistance

- Mar 24, 2018-

Different formulations of drugs must undergo high-temperature drying, sterilization and sterilization or low-temperature lyophilization during the production process, which requires the glass container to have a good and appropriate resistance to sudden changes in temperature without the ability to burst. The temperature-resistance of glass is mainly related to the coefficient of thermal expansion, and the lower the coefficient of thermal expansion, the stronger its ability to resist temperature changes. For example, many high-end vaccine preparations, biological preparations and freeze-dried preparations should generally use 3.3 borosilicate glass or 5.0 borosilicate glass. When a large amount of low-borosilicate glass produced domestically undergoes drastic changes in the temperature difference, it tends to be prone to bursting and falling out of the bottle. In recent years, China's 3.3 borosilicate glass has been greatly developed. This kind of glass is especially suitable for freeze-dried preparations, because its anti-temperature rapid change performance is better than 5.0 borosilicate glass. Good and suitable mechanical strength

Drugs of different formulations need to withstand certain mechanical shock during production and during transportation. The mechanical strength of medicinal glass containers is not only related to the bottle type, geometry, and heat processing, but also the mechanical strength of glass. A certain degree of influence, the mechanical strength of borosilicate glass is better than soda-lime glass